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1

Exploiting arginine auxotrophy with pegylated arginine deiminase (ADI-PEG20) to sensitize pancreatic cancer to radiotherapy via metabolic dysregulation

Singh, Pankaj K, Deorukhkar, Amit A, Venkatesulu, Bhanu P, Li, Xiaolin, Tailor, Ramesh, Bomalaski, John S., Krishnan, Sunil

Journal:

Molecular Cancer Therapeutics

Year:

2019

Language:

english

File:

PDF, 5.10 MB

english, 2019

2

Exploiting arginine auxotrophy with pegylated arginine deiminase (ADI-PEG20) to sensitize pancreatic cancer to radiotherapy via metabolic dysregulation

Singh, Pankaj K, Deorukhkar, Amit A, Venkatesulu, Bhanu P, Li, Xiaolin, Tailor, Ramesh, Bomalaski, John S., Krishnan, Sunil

Journal:

Molecular Cancer Therapeutics

Year:

2019

File:

PDF, 5.10 MB

2019

3

Articular presentation of herpes zoster eruption

Lawrence J. Leventhal, John S. Bomalaski

Journal:

Arthritis & Rheumatism

Year:

1989

Language:

english

File:

PDF, 262 KB

english, 1989

4

Infectious arthritis in renal transplant patients

Dr. John S. Bomalaski, Paul K. Williamson, Carl S. Goldstein

Journal:

Arthritis & Rheumatism

Year:

1986

Language:

english

File:

PDF, 531 KB

english, 1986

5

Enhanced phospholipase activity in peripheral blood monocytes from patients with rheumatoid arthritis

John S. Bomalaski, Mike A. Clark, Robert B. Zurier

Journal:

Arthritis & Rheumatism

Year:

1986

Language:

english

File:

PDF, 646 KB

english, 1986

6

Monosodium urate crystals in the knee joints of patients with asymptomatic nontophaceous gout

John S. Bomalaski, Geronimo Lluberas, H. Ralph Schumacher Jr.

Journal:

Arthritis & Rheumatism

Year:

1986

Language:

english

File:

PDF, 441 KB

english, 1986

7

Incidence and distribution of argininosuccinate synthetase deficiency in human cancers : A method for identifying cancers sensitive to arginine deprivation

Brian J. Dillon, Victor G. Prieto, Steven A. Curley, C. Mark Ensor, Frederick W. Holtsberg, John S. Bomalaski, Mike A. Clark

Journal:

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

8

Regulation of fibroblast proliferation and collagen synthesis by cytokines

Bruce freundlich, John S. Bomalaski, Eric Neilson, Sergio A. Jimenez

Journal:

Immunology Today

Year:

1986

Language:

english

File:

PDF, 449 KB

english, 1986

9

Activation of mechanonociceptors by pro-inflammatory peptides melittin and PLAP peptide

Brian Cooper, John S. Bomalaski

Journal:

Experimental Brain Research

Year:

1994

Language:

english

File:

PDF, 1.17 MB

english, 1994

10

Serum uric acid-lowering therapies: Where are we heading in management of hyperuricemia and the potential role of uricase

John S. Bomalaski, Mike A. Clark

Journal:

Current Rheumatology Reports

Year:

1996

Language:

english

File:

PDF, 435 KB

english, 1996

11

Pegylated arginine deiminase lowers hepatitis C viral titers and inhibits nitric oxide synthesis

Francesco Izzo, Maurizio Montella, Antonio Pio Orlando, Guglielmo Nasti, Gerardo Beneduce, Giuseppe Castello, Francesco Cremona, C. Mark Ensor, Frederick W. Holtzberg, John S. Bomalaski, Mike A. Clark

Journal:

Journal of Gastroenterology and Hepatology

Year:

2007

Language:

english

File:

PDF, 131 KB

english, 2007

12

Analysis of peritoneal macrophages in continuous ambulatory peritoneal dialysis patients

Goldstein, Carl S, Bomalaski, John S, Zurier, Robert B, Neilson, Eric G, Douglas, Steven D

Journal:

Kidney International

Year:

1984

Language:

english

File:

PDF, 870 KB

english, 1984

13

Phase I/II study of pegylated arginine deiminase (ADI-PEG 20) in patients with advanced melanoma

Ott, Patrick A., Carvajal, Richard D., Pandit-Taskar, Neeta, Jungbluth, Achim A., Hoffman, Eric W., Wu, Bor-Wen, Bomalaski, John S., Venhaus, Ralph, Pan, Linda, Old, Lloyd J., Pavlick, Anna C., Wolcho

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 490 KB

english, 2013

14

Phospholipase A2 and arthritis

John S. Bomalaski, Mike A. Clark

Journal:

Arthritis & Rheumatism

Year:

1993

Language:

english

File:

PDF, 840 KB

english, 1993

15

Concomitant activation of extracellular signal-regulated kinase and induction of COX-2 stimulates maximum prostaglandin E2 synthesis in human airway epithelial cells

Nenad Petrovic, Darryl A. Knight, John S. Bomalaski, Philip J. Thompson, Neil L.A. Misso

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2006

Language:

english

File:

PDF, 416 KB

english, 2006

16

Poly(ethylene glycol) (PEG) conjugated arginine deiminase: effects of PEG formulations on its pharmacological properties

Frederick W. Holtsberg, Charles Mark Ensor, Marion R. Steiner, John S. Bomalaski, Mike A. Clark

Journal:

Journal of Controlled Release

Year:

2002

Language:

english

File:

PDF, 458 KB

english, 2002

17

The chief medical residency in the 1980s

John S. Bomalaski, Gary J. Martin

Journal:

The American Journal of Medicine

Year:

1983

Language:

english

File:

PDF, 472 KB

english, 1983

18

Responses of purified phospholipases A2 to phospholipase A2 activating protein (PLAP) and melittin

Marion R. Steiner, John S. Bomalaski, Mike A. Clark

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1993

Language:

english

File:

PDF, 730 KB

english, 1993

19

Antibodies prepared to Bacillus cereus phospholipase C crossreact with a phosphatidylcholine preferring phosoholipase C in mammalian cells

Mike A. Clark, Robert G.L. Shorr, John S. Bomalaski

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 656 KB

english, 1986

20

Alteration of uptake and distribution of eicosanoid precursor fatty acids by aspirin

John S. Bomalaski, Juan Alvarez, Joseph Touchstone, Robert B. Zurier

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 580 KB

english, 1987

21

Phospholipase A2-mediated inflammation induces regression of malignant gliomas

David H. Goddard, John S. Bomalaski, Stanley Lipper, Robert G.L. Shorr, Mike A. Clark

Journal:

Year:

1996

Language:

english

File:

PDF, 608 KB

english, 1996

22

Aspirin inhibits phospholipase C

John S. Bomalaski, Fusao Hirata, Mike A. Clark

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 319 KB

english, 1986

23

Uptake of fatty acids and their mobilization from phospholipids in cultured monocyte-macrophages from rheumatoid arthritis patients

John S. Bomalaski, Carl S. Goldstein, Andrew T. Dailey, Steven D. Douglas, Robert B. Zurier

Journal:

Clinical Immunology and Immunopathology

Year:

1986

Language:

english

File:

PDF, 1001 KB

english, 1986

24

Differential effects of aspirin and dexamethasone on phospolipase A2 and C activities and arachidonic acid release from endothelial cells in respose to bradykinin and leukotriene D4

Mike A. Clark, John S. Bomalaski, Theresa M. Conway, Jill Wartell, Stanley T. Crooke

Journal:

Year:

1986

Language:

english

File:

PDF, 260 KB

english, 1986

25

Binding of leukotriene B4 and its analogs to human polymorphonuclear leukocyte membrane receptors

John S. Bomalaski, Seymour Mong

Journal:

Year:

1987

Language:

english

File:

PDF, 615 KB

english, 1987

26

Evaluation of Arginine Deiminase Treatment in Melanoma Xenografts Using18F-FLT PET

Stelter, Lars, Fuchs, Simon, Jungbluth, Achim A., Ritter, Gerd, Longo, Valerie A., Zanzonico, Pat, Raschzok, Nathanael, Sauer, Igor M., Bomalaski, John S., Larson, Steven M.

Journal:

Molecular Imaging and Biology

Year:

2013

Language:

english

File:

PDF, 695 KB

english, 2013

27

Regulation of synovial cell growth: basic fibroblast growth factor synergizes with interleukin 1β stimulating phospholipase A2 enzyme activity, phospholipase A2 activating protein production and release of prostaglandin E2 by rheumatoid arthritis synovial cells in culture

Goddard, David H., Grossman, Scott L., Newton, Robert, Clark, Mike A., Bomalaski, John S.

Journal:

Year:

1992

Language:

english

File:

PDF, 1020 KB

english, 1992

28

DELAYED PRESENTATION OF POSTERIOR URETHRAL VALVES: A NOT SO BENIGN CONDITION

BOMALASKI, M. DAVID, ANEMA, JOHN G., COPLEN, DOUGLAS E., KOO, HARRY P., ROZANSKI, THOMAS, BLOOM, DAVID A.

Journal:

The Journal of Urology

Year:

1999

Language:

english

File:

PDF, 188 KB

english, 1999

29

DIAGNOSIS AND MANAGEMENT OF VULVAR AND VAGINAL INTRAEPITHELIAL NEOPLASIA

Cardosi, Richard J., Bomalaski, John J., Hoffman, Mitchel S.

Journal:

Obstetrics and Gynecology Clinics of North America

Year:

2001

Language:

english

File:

PDF, 985 KB

english, 2001

30

Salicylate-induced rhabdomyolysis

Leventhal, Lawrence J., Kuritsky, Lloyd, Ginsburg, Richard, Bomalaski, John S.

Journal:

The American Journal of Emergency Medicine

Year:

1989

Language:

english

File:

PDF, 257 KB

english, 1989

31

Separation of Prostaglandins E 1 , and E 2 and other Major Eicosanoids by Unidimensional Argentation Thin Layer Chromatography

Bomalaski, John S., Touchstone, Joseph C., Dailey, Andrew T., Zurier, Robert B.

Journal:

Journal of Liquid Chromatography

Year:

1984

Language:

english

File:

PDF, 478 KB

english, 1984

32

Argininosuccinate synthetase (ASS) deficiency in high-grade pulmonary neuroendocrine carcinoma: an opportunity for personalized targeted therapy

Walts, Ann E., Bomalaski, John S., Ines, Delma, Orsulic, Sandra

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 776 KB

english, 2015

33

Atypical Chest Pain With a Systolic Murmur

Bomalaski, John S.

Journal:

Archives of Internal Medicine

Year:

1983

Language:

english

File:

PDF, 3.69 MB

english, 1983

34

New Heart Murmur and Fever in a Patient With Systemic Lupus Erythematosus

Bomalaski, John

Journal:

Archives of Internal Medicine

Year:

1982

Language:

english

File:

PDF, 1.54 MB

english, 1982

35

Alcohol, Immunosuppression, and the Lung

Bomalaski, John S.

Journal:

Archives of Internal Medicine

Year:

1982

Language:

english

File:

PDF, 255 KB

english, 1982

36

General Internal Medicine Consultation

Bomalaski, John S.

Journal:

Archives of Internal Medicine

Year:

1983

Language:

english

File:

PDF, 301 KB

english, 1983

37

Oculocutaneous Albinism, Platelet Storage Pool Disease, and Progressive Lupus Nephritis

Bomalaski, John S.

Journal:

Archives of Internal Medicine

Year:

1983

Language:

english

File:

PDF, 3.71 MB

english, 1983

38

Cloning of a Phospholipase A2-Activating Protein

Mike A. Clark, Lynne E. Özgür, Theresa M. Conway, Janice Dispoto, Stanley T. Crooke and John S. Bomalaski

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.18 MB

english, 1991

39

Inferior Vena Cava Interruption in the Management of Pulmonary Embolism

Bomalaski, John S., Martin, Gary J., Hughes, Richard L., Yao, James S.T.

Journal:

Year:

1982

Language:

english

File:

PDF, 4.25 MB

english, 1982

40

Mammography

Bomalaski, John J., Tabano, Maggi, Hooper, Lisa, Fiorica, James

Journal:

Current Opinion in Obstetrics & Gynecology

Year:

2001

Language:

english

File:

PDF, 704 KB

english, 2001

41

Differential expression of argininosuccinate synthetase in serous and non-serous ovarian carcinomas

Cheon, Dong-Joo, Walts, Ann E, Beach, Jessica A, Lester, Jenny, Bomalaski, John S, Walsh, Christine S, Ruprecht Wiedemeyer, W, Karlan, Beth Y, Orsulic, Sandra

Journal:

The Journal of Pathology Clinical Research

Year:

2015

Language:

english

File:

PDF, 993 KB

english, 2015

42

Enzymic degradation of plasma arginine using arginine deiminase inhibits nitric oxide production and protects mice from the lethal effects of tumour necrosis factor α and endotoxin

THOMAS, J. Brandon, HOLTSBERG, Frederick W., ENSOR, C. Mark, BOMALASKI, John S., CLARK, Mike A.

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 206 KB

english, 2002

43

Enzymic degradation of plasma arginine using arginine deiminase inhibits nitric oxide production and protects mice from the lethal effects of tumour necrosis factor α and endotoxin

THOMAS, J. Brandon, HOLTSBERG, Frederick W., ENSOR, C. Mark, BOMALASKI, John S., CLARK, Mike A.

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 206 KB

english, 2002

44

A metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas

Bean, Gregory R, Kremer, Jeff C, Prudner, Bethany C, Schenone, Aaron D, Yao, Juo-Chin, Schultze, Matthew B, Chen, David Y, Tanas, Munir R, Adkins, Douglas R, Bomalaski, John, Rubin, Brian P, Michel, L

Journal:

Cell Death and Disease

Year:

2016

Language:

english

File:

PDF, 2.84 MB

english, 2016

45

Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase–Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase

Sahu, Divya, Gupta, Sounak, Hau, Andrew M., Nakashima, Kazufumi, Leivo, Mariah Z., Searles, Stephen C., Elson, Paul, Bomalaski, John S., Casteel, Darren E., Boss, Gerry R., Hansel, Donna E.

Journal:

The American Journal of Pathology

Year:

2017

Language:

english

File:

PDF, 2.83 MB

english, 2017

46

Uricase formulated with polyethylene glycol (Uricase-PEG 20): Biochemical rationale and preclinical studies

Bomalaski, John S., Holtsberg, Frederick W., Ensor, C. Mark, Clark, Mike a.

Journal:

The Journal of Rheumatology

Year:

2002

Language:

english

File:

PDF, 537 KB

english, 2002

47

Thrombocytopenia in a Prospective, Randomized, Double-Blind Trial of Bovine and Porcine Heparin

Green, David, Martin, Gary J., Shoichet, Sandor H., Debacker, Noel, Bomalaski, John S., Lind, Richard N.

Journal:

The American Journal of the Medical Sciences

Year:

1984

File:

PDF, 437 KB

1984

48

A phase 1/1B trial of ADI-PEG 20 plus nab-paclitaxel and gemcitabine in patients with advanced pancreatic adenocarcinoma

Lowery, Maeve A., Yu, Kenneth H., Kelsen, David Paul, Harding, James J., Bomalaski, John S., Glassman, Danielle C., Covington, Christina M., Brenner, Robin, Hollywood, Ellen, Barba, Adalberto, Johnsto

Journal:

Year:

2017

Language:

english

File:

PDF, 428 KB

english, 2017

49

A Phase II Study of Arginine Deiminase (ADI-PEG20) in Relapsed/Refractory or Poor-Risk Acute Myeloid Leukemia Patients

Tsai, Hui-Jen, Jiang, Shih Sheng, Hung, Wen-Chun, Borthakur, Gautam, Lin, Sheng-Fung, Pemmaraju, Naveen, Jabbour, Elias, Bomalaski, John S., Chen, Ya-Ping, Hsiao, Hui-Hua, Wang, Ming-Chung, Kuo, Ching

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017

50

Argininosuccinate Synthetase-1 (ASS1) Loss in High-Grade Neuroendocrine Carcinomas of the Urinary Bladder: Implications for Targeted Therapy with ADI-PEG 20

Gupta, Sounak, Sahu, Divya, Bomalaski, John S., Frank, Igor, Boorjian, Stephen A., Thapa, Prabin, Cheville, John C., Hansel, Donna E.

Journal:

Endocrine Pathology

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

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